Melatonin and jet lag

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Melatonin for the prevention and treatment of jet lag.

BACKGROUND : Jet-lag commonly affects air travellers who cross several time zones. It results from the body's internal rhythms being out of step with the day-night cycle at the destination. Melatonin is a pineal hormone that plays a central part in regulating bodily rhythms and has been used as a drug to re-align them with the outside world. OBJECTIVES : To assess the effectiveness of oral me...

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Jet-lag and shift work: (2). Therapeutic use of melatonin.

The preceding article1 has laid the foundations for understanding the difficulties of jet-lag and shiftworker's malaise and for appreciating the various countermeasures other than chronobiotics (drugs that alter rhythms). Several approaches have met with some success. One of the major difficulties in this area is the uncontrollable nature of field studies on jet-lag and our inability to simulat...

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Effect of melatonin on jet lag after long haul flights.

OBJECTIVE To determine whether doses of the pineal hormone melatonin alleviate jet lag. DESIGN Double blind, placebo controlled crossover trial. SETTING Long haul return flights from Auckland, New Zealand, to London and back. SUBJECTS Twenty volunteers with experience of transcontinental flights (eight women and 12 men aged 28 to 68). INTERVENTIONS Melatonin (or placebo) 5 mg three days...

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Jet lag.

INTRODUCTION Jet lag affects most air travellers crossing five or more time zones; it tends to be worse on eastward than on westward flights. METHODS AND OUTCOMES We conducted a systematic review and aimed to answer the following clinical question: What are the effects of interventions to prevent or minimise jet lag? We searched: Medline, Embase, The Cochrane Library, and other important data...

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ژورنال

عنوان ژورنال: British Journal of Sports Medicine

سال: 1998

ISSN: 0306-3674

DOI: 10.1136/bjsm.32.2.98